ECEL1
Gene Information
- Official Symbol: ECEL1
- Official Name: endothelin converting enzyme like 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 9427
- UniProt: O95672
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the M13 family of endopeptidases. Members of this family are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. Mutations in this gene are associated with autosomal recessive distal arthrogryposis, type 5D. This gene has multiple pseudogenes on chromosome 2. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014].
- UniProt Summary: May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 3639
- Expression level (log2 read counts): -4.14
ECEL1 Expression in NALM6 Cells: -4.14
