Entrez Summary: Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015].
UniProt Summary: N/A
Pfam DomainsGO Terms
Pfam Domains
FERM M
FERM N
4 1 CTD
SAB
FA
FERM C
GO Terms
cortical actin cytoskeleton organization
cortical cytoskeleton organization
actomyosin structure organization
structural molecule activity
actin binding
cytoskeleton
actin cytoskeleton organization
actin filament-based process
cytoskeleton organization
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)