FNBP4
Gene Information
- Official Symbol: FNBP4
- Official Name: formin binding protein 4
- Aliases and Previous Symbols: N/A
- Entrez ID: 23360
- UniProt: Q8N3X1
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a protein containing two tryptophan-rich WW domains that binds the proline-rich formin homology 1 domains of formin family proteins, suggesting a role in the regulation of cytoskeletal dynamics during cell division and migration. It also binds intersectin family proteins suggesting a role in the maintenance of membrane curvature at sites of nascent vesicle formation. Naturally occurring mutations in this gene are associated with Waardenburg anophthalmia syndrome. [provided by RefSeq, Apr 2017].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 1728
- Expression level (log2 read counts): 7.61
FNBP4 Expression in NALM6 Cells: 7.61
