UniProt Summary: May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium. {ECO:0000250|UniProtKB:A1EGX6}.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
negative regulation of protein sumoylation
regulation of protein sumoylation
negative regulation of protein modification by small protein conjugation or removal
motile cilium
regulation of protein modification by small protein conjugation or removal
negative regulation of protein modification process
negative regulation of cellular protein metabolic process
negative regulation of protein metabolic process
regulation of protein modification process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739