FUT10
Gene Information
- Official Symbol: FUT10
- Official Name: fucosyltransferase 10
- Aliases and Previous Symbols: N/A
- Entrez ID: 84750
- UniProt: Q6P4F1
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Probable fucosyltransferase. {ECO:0000250}.
Pfam Domains GO Terms
Pfam Domains
| Glyco transf 10 |
GO Terms
| alpha-(1→3)-fucosyltransferase activity |
| L-fucose catabolic process |
| fucose catabolic process |
| L-fucose metabolic process |
| fucose metabolic process |
| fucosylation |
| neuronal stem cell population maintenance |
| cerebral cortex radially oriented cell migration |
| cerebral cortex cell migration |
| hexose catabolic process |
| telencephalon cell migration |
| forebrain cell migration |
| monosaccharide catabolic process |
| Golgi cisterna membrane |
| cerebral cortex development |
| carbohydrate catabolic process |
| stem cell population maintenance |
| maintenance of cell number |
| hexose metabolic process |
| fertilization |
| pallium development |
| monosaccharide metabolic process |
| protein folding |
| telencephalon development |
| protein glycosylation |
| macromolecule glycosylation |
| glycosylation |
| glycoprotein biosynthetic process |
| protein targeting |
| glycoprotein metabolic process |
| forebrain development |
| small molecule catabolic process |
| carbohydrate metabolic process |
| wound healing |
| hemopoiesis |
| response to wounding |
| hematopoietic or lymphoid organ development |
| carbohydrate derivative biosynthetic process |
| immune system development |
| brain development |
| head development |
| sexual reproduction |
| cell migration |
| central nervous system development |
| Golgi apparatus |
| intracellular protein transport |
| multi-organism reproductive process |
| endoplasmic reticulum |
| carbohydrate derivative metabolic process |
| cell motility |
| localization of cell |
| locomotion |
| organonitrogen compound biosynthetic process |
| reproductive process |
| reproduction |
| protein transport |
| intracellular transport |
| peptide transport |
| movement of cell or subcellular component |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| cellular macromolecule biosynthetic process |
| small molecule metabolic process |
| macromolecule biosynthetic process |
| organic substance catabolic process |
| establishment of localization in cell |
| nitrogen compound transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Milciclib 2μM R08 exp502 | -1.97 |
| Cadmium 60μM R08 exp462 | 1.92 |
| TGF-beta1 44ng/ml R08 exp528 | 2.21 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 12700
- Expression level (log2 read counts): 4.68
Expression Distribution
FUT10 Expression in NALM6 Cells: 4.68
