GABRA3
Gene Information
- Official Symbol: GABRA3
- Official Name: gamma-aminobutyric acid type A receptor subunit alpha3
- Aliases and Previous Symbols: N/A
- Entrez ID: 2556
- UniProt: P34903
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008].
- UniProt Summary: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 17473
- Expression level (log2 read counts): -2.47
GABRA3 Expression in NALM6 Cells: -2.47
