Pfam Domains GO Terms
| CAP |
| positive regulation of epithelial to mesenchymal transition |
| regulation of epithelial to mesenchymal transition |
| positive regulation of epithelial cell migration |
| positive regulation of ERK1 and ERK2 cascade |
| regulation of epithelial cell migration |
| regulation of ERK1 and ERK2 cascade |
| positive regulation of cell migration |
| positive regulation of cell motility |
| positive regulation of cellular component movement |
| positive regulation of MAPK cascade |
| positive regulation of locomotion |
| Golgi membrane |
| regulation of MAPK cascade |
| regulation of cell migration |
| protein homodimerization activity |
| regulation of cell motility |
| positive regulation of cell differentiation |
| regulation of locomotion |
| regulation of cellular component movement |
| positive regulation of protein phosphorylation |
| positive regulation of intracellular signal transduction |
| positive regulation of phosphorylation |
| positive regulation of phosphate metabolic process |
| positive regulation of phosphorus metabolic process |
| positive regulation of protein modification process |
| positive regulation of developmental process |
| regulation of protein phosphorylation |
| regulation of phosphorylation |
| extracellular space |
| positive regulation of cellular protein metabolic process |
| positive regulation of signal transduction |
| positive regulation of protein metabolic process |
| positive regulation of multicellular organismal process |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| regulation of cell differentiation |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of intracellular signal transduction |
| regulation of protein modification process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution