UniProt Summary: This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Pfam DomainsGO Terms
Pfam Domains
HRM
7tm 2
GO Terms
glucagon receptor activity
cellular response to glucagon stimulus
response to glucagon
G protein-coupled peptide receptor activity
peptide hormone binding
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
cellular response to peptide hormone stimulus
cellular response to peptide
response to peptide hormone
response to peptide
cellular response to organonitrogen compound
cellular response to hormone stimulus
cellular response to nitrogen compound
G protein-coupled receptor activity
response to hormone
positive regulation of cell population proliferation
response to organonitrogen compound
cellular response to oxygen-containing compound
response to nitrogen compound
cellular response to endogenous stimulus
G protein-coupled receptor signaling pathway
response to endogenous stimulus
response to oxygen-containing compound
regulation of cell population proliferation
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739