UniProt Summary: Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity). {ECO:0000250|UniProtKB:P63153, ECO:0000250|UniProtKB:Q8R1I2}.
Pfam DomainsGO Terms
Pfam Domains
Bombesin
GO Terms
positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway
psychomotor behavior
regulation of phospholipase C-activating G protein-coupled receptor signaling pathway
motor behavior
neuropeptide hormone activity
positive regulation of G protein-coupled receptor signaling pathway
social behavior
intraspecies interaction between organisms
multi-organism behavior
positive regulation of peptide hormone secretion
neuropeptide signaling pathway
secretory granule lumen
positive regulation of hormone secretion
regulation of G protein-coupled receptor signaling pathway
regulation of peptide hormone secretion
regulation of hormone secretion
positive regulation of peptide secretion
signaling receptor binding
positive regulation of secretion by cell
positive regulation of secretion
regulation of peptide secretion
regulation of hormone levels
behavior
regulation of peptide transport
regulation of secretion by cell
regulation of secretion
positive regulation of transport
response to external biotic stimulus
G protein-coupled receptor signaling pathway
response to biotic stimulus
extracellular space
positive regulation of signal transduction
positive regulation of cell communication
positive regulation of signaling
regulation of transport
extracellular region
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739