HDHD1
Gene Information
- Official Symbol: PUDP
- Official Name: pseudouridine 5'-phosphatase
- Aliases and Previous Symbols: N/A
- Entrez ID: 8226
- UniProt: Q08623
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the haloacid dehalogenase-like (HAD) hydrolase superfamily. The encoded protein has no known biological function. This gene has a pseudogene on chromosome 1. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010].
- UniProt Summary: Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine. {ECO:0000269|PubMed:20722631}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 15345
- Expression level (log2 read counts): 3.68
HDHD1 Expression in NALM6 Cells: 3.68
