Pfam Domains GO Terms
| C1-set |
| MHC II beta |
| MHC class II protein complex |
| integral component of lumenal side of endoplasmic reticulum membrane |
| clathrin-coated endocytic vesicle membrane |
| peptide antigen binding |
| transport vesicle membrane |
| ER to Golgi transport vesicle membrane |
| endocytic vesicle membrane |
| interferon-gamma-mediated signaling pathway |
| trans-Golgi network membrane |
| antigen processing and presentation of exogenous peptide antigen via MHC class II |
| antigen processing and presentation of peptide antigen via MHC class II |
| antigen processing and presentation of peptide or polysaccharide antigen via MHC class II |
| late endosome membrane |
| cellular response to interferon-gamma |
| T cell receptor signaling pathway |
| antigen processing and presentation of exogenous peptide antigen |
| response to interferon-gamma |
| antigen processing and presentation of exogenous antigen |
| antigen processing and presentation of peptide antigen |
| antigen processing and presentation |
| antigen receptor-mediated signaling pathway |
| lysosomal membrane |
| immune response-activating cell surface receptor signaling pathway |
| immune response-regulating cell surface receptor signaling pathway |
| immune response-activating signal transduction |
| immune response-regulating signaling pathway |
| adaptive immune response |
| Golgi membrane |
| activation of immune response |
| cytokine-mediated signaling pathway |
| innate immune response |
| positive regulation of immune response |
| defense response to other organism |
| cellular response to cytokine stimulus |
| response to cytokine |
| regulation of immune response |
| positive regulation of immune system process |
| response to other organism |
| response to external biotic stimulus |
| response to biotic stimulus |
| defense response |
| regulation of immune system process |
| immune response |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| CCT251545 20μM R07 exp326 | -1.93 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution