HOXB6
Gene Information
- Official Symbol: HOXB6
- Official Name: homeobox B6
- Aliases and Previous Symbols: N/A
- Entrez ID: 3216
- UniProt: P17509
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer. [provided by RefSeq, Jul 2008].
- UniProt Summary: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 11850
- Expression level (log2 read counts): -1.76
HOXB6 Expression in NALM6 Cells: -1.76
