HSF2BP
Gene Information
- Official Symbol: HSF2BP
- Official Name: heat shock transcription factor 2 binding protein
- Aliases and Previous Symbols: N/A
- Entrez ID: 11077
- UniProt: O75031
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: HSF2 binding protein (HSF2BP) associates with HSF2. The interaction occurs between the trimerization domain of HSF2 and the amino terminal hydrophilic region of HSF2BP that comprises two leucine zipper motifs. HSF2BP may therefore be involved in modulating HSF2 activation. [provided by RefSeq, Jul 2008].
- UniProt Summary: May be involved in modulating HSF2 activation in testis (PubMed:9651507). Inhibits BNC1 transcriptional activity during spermatogenesis, probably by sequestering it in the cytoplasm (By similarity). {ECO:0000250|UniProtKB:Q9D4G2, ECO:0000269|PubMed:9651507}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 12417
- Expression level (log2 read counts): -0.25
HSF2BP Expression in NALM6 Cells: -0.25
