Pfam Domains GO Terms
| Hus1 |
| meiotic DNA integrity checkpoint |
| checkpoint clamp complex |
| meiotic cell cycle checkpoint |
| mitotic DNA replication checkpoint |
| intra-S DNA damage checkpoint |
| DNA replication checkpoint |
| mitotic G2/M transition checkpoint |
| site of double-strand break |
| negative regulation of G2/M transition of mitotic cell cycle |
| mitotic DNA damage checkpoint |
| double-strand break repair via homologous recombination |
| recombinational repair |
| telomere maintenance |
| negative regulation of cell cycle G2/M phase transition |
| telomere organization |
| mitotic DNA integrity checkpoint |
| nucleotide-excision repair |
| DNA damage checkpoint |
| DNA integrity checkpoint |
| mitotic cell cycle checkpoint |
| meiotic cell cycle process |
| double-strand break repair |
| cell cycle checkpoint |
| regulation of G2/M transition of mitotic cell cycle |
| regulation of cell cycle G2/M phase transition |
| negative regulation of mitotic cell cycle phase transition |
| DNA recombination |
| meiotic cell cycle |
| negative regulation of cell cycle phase transition |
| negative regulation of mitotic cell cycle |
| negative regulation of cell cycle process |
| anatomical structure homeostasis |
| regulation of mitotic cell cycle phase transition |
| regulation of cell cycle phase transition |
| DNA repair |
| negative regulation of cell cycle |
| mitotic cell cycle process |
| regulation of mitotic cell cycle |
| mitotic cell cycle |
| DNA metabolic process |
| regulation of cell cycle process |
| cellular response to DNA damage stimulus |
| nucleolus |
| cell cycle process |
| chromosome organization |
| regulation of cell cycle |
| cell cycle |
| reproductive process |
| reproduction |
| homeostatic process |
| cellular response to stress |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Golgicide-A 2μM R03 exp121 | 2.16 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution