UniProt Summary: Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 (PubMed:19074135). {ECO:0000269|PubMed:19074135}.
Pfam DomainsGO Terms
Pfam Domains
Ion trans
K tetra
Ion trans 2
GO Terms
delayed rectifier potassium channel activity
voltage-gated potassium channel activity
voltage-gated potassium channel complex
ion channel binding
potassium ion transmembrane transport
potassium ion transport
protein homooligomerization
monovalent inorganic cation transport
regulation of ion transmembrane transport
protein complex oligomerization
inorganic cation transmembrane transport
regulation of transmembrane transport
cation transmembrane transport
metal ion transport
inorganic ion transmembrane transport
regulation of ion transport
cation transport
ion transmembrane transport
transmembrane transport
ion transport
protein-containing complex assembly
protein-containing complex subunit organization
regulation of transport
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739