UniProt Summary: Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane.
Pfam DomainsGO Terms
Pfam Domains
Ion trans 2
GO Terms
potassium ion leak channel activity
stabilization of membrane potential
potassium channel activity
voltage-gated ion channel activity
potassium ion transmembrane transport
potassium ion transport
monovalent inorganic cation transport
regulation of membrane potential
regulation of ion transmembrane transport
inorganic cation transmembrane transport
regulation of transmembrane transport
cation transmembrane transport
metal ion transport
inorganic ion transmembrane transport
regulation of ion transport
cation transport
ion transmembrane transport
transmembrane transport
ion transport
integral component of plasma membrane
regulation of transport
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739