KLC2
Gene Information
- Official Symbol: KLC2
- Official Name: kinesin light chain 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 64837
- UniProt: Q9H0B6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is a light chain of kinesin, a molecular motor responsible for moving vesicles and organelles along microtubules. Defects in this gene are a cause of spastic paraplegia, optic atrophy, and neuropathy (SPOAN) syndrome. [provided by RefSeq, Mar 2016].
- UniProt Summary: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity). {ECO:0000250}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 9397
- Expression level (log2 read counts): 4.95
KLC2 Expression in NALM6 Cells: 4.95
