LRG1
Gene Information
- Official Symbol: LRG1
- Official Name: leucine rich alpha-2-glycoprotein 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 116844
- UniProt: P02750
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| LRR 4 |
GO Terms
| brown fat cell differentiation |
| positive regulation of cellular response to transforming growth factor beta stimulus |
| positive regulation of transforming growth factor beta receptor signaling pathway |
| transforming growth factor beta receptor binding |
| tertiary granule lumen |
| specific granule lumen |
| positive regulation of endothelial cell proliferation |
| positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway |
| fat cell differentiation |
| regulation of transforming growth factor beta receptor signaling pathway |
| regulation of cellular response to transforming growth factor beta stimulus |
| ficolin-1-rich granule lumen |
| regulation of endothelial cell proliferation |
| positive regulation of angiogenesis |
| positive regulation of vasculature development |
| positive regulation of epithelial cell proliferation |
| regulation of transmembrane receptor protein serine/threonine kinase signaling pathway |
| regulation of cellular response to growth factor stimulus |
| regulation of angiogenesis |
| regulation of vasculature development |
| regulation of epithelial cell proliferation |
| neutrophil degranulation |
| neutrophil activation involved in immune response |
| neutrophil mediated immunity |
| neutrophil activation |
| granulocyte activation |
| leukocyte degranulation |
| myeloid leukocyte mediated immunity |
| myeloid cell activation involved in immune response |
| myeloid leukocyte activation |
| leukocyte activation involved in immune response |
| cell activation involved in immune response |
| intracellular membrane-bounded organelle |
| response to bacterium |
| regulated exocytosis |
| molecular function |
| leukocyte mediated immunity |
| exocytosis |
| positive regulation of cell population proliferation |
| leukocyte activation |
| secretion by cell |
| export from cell |
| regulation of anatomical structure morphogenesis |
| cell activation |
| immune effector process |
| secretion |
| response to other organism |
| response to external biotic stimulus |
| response to biotic stimulus |
| positive regulation of developmental process |
| extracellular space |
| regulation of cell population proliferation |
| positive regulation of signal transduction |
| positive regulation of multicellular organismal process |
| positive regulation of cell communication |
| positive regulation of signaling |
| immune response |
| extracellular region |
| vesicle-mediated transport |
| membrane |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 6931
- Expression level (log2 read counts): 2.72
Expression Distribution
LRG1 Expression in NALM6 Cells: 2.72
