LYVE1
Gene Information
- Official Symbol: LYVE1
- Official Name: lymphatic vessel endothelial hyaluronan receptor 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 10894
- UniProt: Q9Y5Y7
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. {ECO:0000269|PubMed:10037799}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 9076
- Expression level (log2 read counts): -2.21
LYVE1 Expression in NALM6 Cells: -2.21
