UniProt Summary: May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (By similarity). {ECO:0000250}.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
retina layer formation
retina morphogenesis in camera-type eye
neural retina development
homotypic cell-cell adhesion
camera-type eye morphogenesis
retina development in camera-type eye
eye morphogenesis
basolateral plasma membrane
sensory organ morphogenesis
camera-type eye development
eye development
visual system development
sensory system development
cell-cell adhesion
sensory organ development
anatomical structure formation involved in morphogenesis
cell adhesion
biological adhesion
animal organ morphogenesis
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739