MYH8
Gene Information
- Official Symbol: MYH8
- Official Name: myosin heavy chain 8
- Aliases and Previous Symbols: N/A
- Entrez ID: 4626
- UniProt: P13535
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is predominantly expressed in fetal skeletal muscle. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in trismus-pseudocamptodactyly syndrome. [provided by RefSeq, Sep 2009].
- UniProt Summary: Muscle contraction.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 5918
- Expression level (log2 read counts): -3.9
MYH8 Expression in NALM6 Cells: -3.9
