Entrez Summary: The protein encoded by this gene is a proteolipid that may be involved in the regulation of ion channels during brain development. The encoded protein may also play a role in forming and maintaining the structure of the nervous system. This gene is found within an intron of another gene, bladder cancer associated protein, but on the opposite strand. This gene is imprinted and is expressed only from the paternal allele. [provided by RefSeq, Apr 2016].
UniProt Summary: May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system. May function as a regulatory subunit of ion channels.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
protein lipoylation
protein-cofactor linkage
positive regulation of insulin secretion
positive regulation of peptide hormone secretion
positive regulation of hormone secretion
regulation of insulin secretion
regulation of peptide hormone secretion
protein maturation
regulation of hormone secretion
positive regulation of protein secretion
positive regulation of peptide secretion
peptidyl-lysine modification
positive regulation of secretion by cell
positive regulation of protein transport
positive regulation of secretion
positive regulation of establishment of protein localization
regulation of protein secretion
regulation of peptide secretion
regulation of hormone levels
regulation of protein transport
regulation of peptide transport
brain development
regulation of establishment of protein localization
regulation of secretion by cell
head development
regulation of secretion
peptidyl-amino acid modification
central nervous system development
positive regulation of transport
neuron differentiation
regulation of protein localization
generation of neurons
neurogenesis
positive regulation of cell communication
positive regulation of signaling
regulation of transport
gene expression
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739