UniProt Summary: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
Pfam DomainsGO Terms
Pfam Domains
7TM GPCR Srsx
7tm 1
GO Terms
opioid receptor activity
opioid receptor signaling pathway
neuropeptide receptor activity
neuropeptide binding
peptide binding
neuropeptide signaling pathway
anterograde trans-synaptic signaling
chemical synaptic transmission
trans-synaptic signaling
synaptic signaling
G protein-coupled receptor activity
cell-cell signaling
G protein-coupled receptor signaling pathway
integral component of plasma membrane
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)