NTNG1
Gene Information
- Official Symbol: NTNG1
- Official Name: netrin G1
- Aliases and Previous Symbols: N/A
- Entrez ID: 22854
- UniProt: Q9Y2I2
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a preproprotein that is processed into a secreted protein containing eukaroytic growth factor (EGF)-like domains. This protein acts to guide axon growth during neuronal development. Polymorphisms in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2015].
- UniProt Summary: Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites. {ECO:0000269|PubMed:21946559}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 11640
- Expression level (log2 read counts): -0.82
NTNG1 Expression in NALM6 Cells: -0.82
