Pfam Domains GO Terms
| 7tm 1 |
| G protein-coupled serotonin receptor activity |
| G protein-coupled serotonin receptor signaling pathway |
| neurotransmitter receptor activity |
| serotonin receptor signaling pathway |
| cellular response to dopamine |
| response to dopamine |
| signal transduction involved in cellular response to ammonium ion |
| cellular response to monoamine stimulus |
| cellular response to catecholamine stimulus |
| response to catecholamine |
| response to monoamine |
| cellular response to ammonium ion |
| response to ammonium ion |
| G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
| cellular response to drug |
| dendrite |
| anterograde trans-synaptic signaling |
| chemical synaptic transmission |
| trans-synaptic signaling |
| detection of chemical stimulus involved in sensory perception of smell |
| olfactory receptor activity |
| synaptic signaling |
| sensory perception of smell |
| detection of chemical stimulus involved in sensory perception |
| detection of chemical stimulus |
| sensory perception of chemical stimulus |
| cellular response to organic cyclic compound |
| detection of stimulus involved in sensory perception |
| cellular response to organonitrogen compound |
| cellular response to nitrogen compound |
| detection of stimulus |
| G protein-coupled receptor activity |
| response to organic cyclic compound |
| sensory perception |
| response to organonitrogen compound |
| response to drug |
| cellular response to oxygen-containing compound |
| response to nitrogen compound |
| cell-cell signaling |
| cellular response to endogenous stimulus |
| G protein-coupled receptor signaling pathway |
| nervous system process |
| integral component of plasma membrane |
| response to endogenous stimulus |
| response to oxygen-containing compound |
| system process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Lead acetate 990μM R08 exp496 | -1.88 |
| Salinomycin 3.5μM R08 exp521 | -1.85 |
| CCT251545 20μM R07 exp326 | -1.74 |
| Arsenic trioxide 60μM R08 exp449 | -1.72 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution