UniProt Summary: Functions as a modulator of calcium-binding by calmodulin. Thereby, regulates calmodulin activity and the different processes it controls (PubMed:19106096, PubMed:23204517, PubMed:27876793). For instance, may play a role in neuronal differentiation through activation of calmodulin-dependent kinase signaling pathways (PubMed:21491429). {ECO:0000269|PubMed:19106096, ECO:0000269|PubMed:21491429, ECO:0000269|PubMed:23204517, ECO:0000269|PubMed:27876793}.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
calmodulin dependent kinase signaling pathway
calmodulin binding
positive regulation of neuron differentiation
positive regulation of neurogenesis
positive regulation of nervous system development
positive regulation of cell development
protein-containing complex
regulation of neuron differentiation
calcium ion binding
regulation of neurogenesis
regulation of nervous system development
regulation of cell development
positive regulation of cell differentiation
positive regulation of developmental process
generation of neurons
neurogenesis
positive regulation of multicellular organismal process
regulation of cell differentiation
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739