UniProt Summary: Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle (By similarity). {ECO:0000250}.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
wound healing, spreading of epidermal cells
epiboly involved in wound healing
wound healing, spreading of cells
epiboly
negative regulation of cell-matrix adhesion
morphogenesis of an epithelial sheet
negative regulation of cell-substrate adhesion
anchored component of membrane
regulation of cell-matrix adhesion
regulation of cell-substrate adhesion
negative regulation of cell adhesion
apical plasma membrane
external side of plasma membrane
morphogenesis of an epithelium
wound healing
positive regulation of cell migration
positive regulation of cell motility
positive regulation of cellular component movement
positive regulation of locomotion
tissue morphogenesis
response to wounding
regulation of cell adhesion
regulation of cell migration
regulation of cell motility
cell migration
regulation of locomotion
regulation of cellular component movement
localization of cell
cell motility
epithelium development
locomotion
movement of cell or subcellular component
tissue development
extracellular region
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)