Pfam Domains GO Terms
| RBD-FIP |
| negative regulation of adiponectin secretion |
| regulation of adiponectin secretion |
| ADP-ribosylation factor binding |
| dynein light intermediate chain binding |
| endocytic recycling |
| regulation of endocrine process |
| protein localization to cilium |
| cleavage furrow |
| endocytic vesicle |
| intercellular bridge |
| negative regulation of hormone secretion |
| recycling endosome membrane |
| regulation of cytokinesis |
| recycling endosome |
| negative regulation of protein secretion |
| negative regulation of peptide secretion |
| Rab GTPase binding |
| midbody |
| microtubule organizing center |
| regulation of cell division |
| negative regulation of protein transport |
| negative regulation of establishment of protein localization |
| negative regulation of secretion by cell |
| endosomal transport |
| negative regulation of secretion |
| regulation of hormone secretion |
| endosome |
| regulation of protein secretion |
| negative regulation of transport |
| centrosome |
| cell division |
| regulation of peptide secretion |
| regulation of hormone levels |
| regulation of system process |
| intracellular membrane-bounded organelle |
| regulation of protein transport |
| calcium ion binding |
| protein localization to organelle |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| regulation of secretion by cell |
| regulation of cell cycle process |
| regulation of secretion |
| protein homodimerization activity |
| regulation of protein localization |
| regulation of cell cycle |
| negative regulation of multicellular organismal process |
| cell cycle |
| negative regulation of cell communication |
| negative regulation of signaling |
| intracellular transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of localization in cell |
| regulation of transport |
| vesicle-mediated transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| DABN 2μM R00 exp16 | -2.03 |
| 5-Fluorouracil 2μM R00 exp1 | -1.78 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution