RAB3B
Gene Information
- Official Symbol: RAB3B
- Official Name: RAB3B, member RAS oncogene family
- Aliases and Previous Symbols: N/A
- Entrez ID: 5865
- UniProt: P20337
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Protein transport. Probably involved in vesicular traffic (By similarity). {ECO:0000250}.
Pfam Domains GO Terms
Pfam Domains
| Arf |
| Miro |
| Ras |
GO Terms
| peptidyl-cysteine methylation |
| positive regulation of catecholamine uptake involved in synaptic transmission |
| positive regulation of dopamine uptake involved in synaptic transmission |
| regulation of vesicle size |
| positive regulation of neurotransmitter uptake |
| positive regulation of synaptic transmission, dopaminergic |
| regulation of dopamine uptake involved in synaptic transmission |
| regulation of catecholamine uptake involved in synaptic transmission |
| dopaminergic synapse |
| anchored component of synaptic vesicle membrane |
| regulation of synaptic transmission, dopaminergic |
| myosin V binding |
| regulation of neurotransmitter uptake |
| GTP-dependent protein binding |
| positive regulation of response to drug |
| positive regulation of amine transport |
| peptidyl-cysteine modification |
| positive regulation of neurotransmitter transport |
| vesicle docking involved in exocytosis |
| vesicle docking |
| exocytic process |
| Rab protein signal transduction |
| GDP binding |
| secretory granule |
| regulation of amine transport |
| regulation of response to drug |
| regulation of synaptic vesicle cycle |
| synaptic vesicle |
| protein methylation |
| protein alkylation |
| vesicle |
| regulation of neurotransmitter transport |
| positive regulation of synaptic transmission |
| protein secretion |
| establishment of protein localization to extracellular region |
| protein localization to extracellular region |
| organelle localization by membrane tethering |
| peptide secretion |
| membrane docking |
| protein localization to plasma membrane |
| antigen processing and presentation |
| regulation of exocytosis |
| protein localization to cell periphery |
| Ras protein signal transduction |
| macromolecule methylation |
| endosome |
| positive regulation of ion transport |
| methylation |
| small GTPase mediated signal transduction |
| GTPase activity |
| regulation of neurotransmitter levels |
| regulation of cellular component size |
| GTP binding |
| modulation of chemical synaptic transmission |
| regulation of trans-synaptic signaling |
| protein localization to membrane |
| regulation of anatomical structure size |
| regulation of vesicle-mediated transport |
| organelle localization |
| perinuclear region of cytoplasm |
| regulation of ion transport |
| regulation of secretion by cell |
| exocytosis |
| regulation of secretion |
| peptidyl-amino acid modification |
| regulation of cellular localization |
| Golgi apparatus |
| positive regulation of transport |
| intracellular protein transport |
| secretion by cell |
| export from cell |
| secretion |
| protein transport |
| intracellular transport |
| peptide transport |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| intracellular signal transduction |
| positive regulation of cell communication |
| positive regulation of signaling |
| establishment of localization in cell |
| nitrogen compound transport |
| regulation of transport |
| vesicle-mediated transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 11178
- Expression level (log2 read counts): 3.84
Expression Distribution
RAB3B Expression in NALM6 Cells: 3.84
