UniProt Summary: Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity). {ECO:0000250}.
Pfam DomainsGO Terms
Pfam Domains
RasGEF
GO Terms
regulation of Ral protein signal transduction
guanyl-nucleotide exchange factor activity
regulation of Ras protein signal transduction
small GTPase mediated signal transduction
regulation of small GTPase mediated signal transduction
intracellular signal transduction
regulation of intracellular signal transduction
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)