RGS1
Gene Information
- Official Symbol: RGS1
- Official Name: regulator of G protein signaling 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 5996
- UniProt: Q08116
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors (PubMed:10480894). Inhibits B cell chemotaxis toward CXCL12 (By similarity). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (PubMed:10480894, PubMed:18434541). {ECO:0000250|UniProtKB:Q9JL25, ECO:0000269|PubMed:10480894, ECO:0000269|PubMed:18434541}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 15823
- Expression level (log2 read counts): -3.59
RGS1 Expression in NALM6 Cells: -3.59
