RNF123
Gene Information
- Official Symbol: RNF123
- Official Name: ring finger protein 123
- Aliases and Previous Symbols: N/A
- Entrez ID: 63891
- UniProt: Q5XPI4
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 4591
- Expression level (log2 read counts): 5.92
RNF123 Expression in NALM6 Cells: 5.92
