Pfam Domains GO Terms
| Ribosomal L24e |
| assembly of large subunit precursor of preribosome |
| exit from mitosis |
| optic nerve development |
| retinal ganglion cell axon guidance |
| ribosomal large subunit assembly |
| polysomal ribosome |
| cranial nerve development |
| ribosome assembly |
| cytosolic large ribosomal subunit |
| ribosomal large subunit biogenesis |
| cytoplasmic translation |
| nerve development |
| SRP-dependent cotranslational protein targeting to membrane |
| cotranslational protein targeting to membrane |
| protein targeting to ER |
| establishment of protein localization to endoplasmic reticulum |
| viral transcription |
| nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| viral gene expression |
| protein localization to endoplasmic reticulum |
| retina development in camera-type eye |
| translational initiation |
| mitotic nuclear division |
| mitotic cell cycle checkpoint |
| protein targeting to membrane |
| structural constituent of ribosome |
| cell cycle checkpoint |
| nuclear-transcribed mRNA catabolic process |
| mRNA catabolic process |
| ribonucleoprotein complex assembly |
| ribonucleoprotein complex subunit organization |
| RNA catabolic process |
| axon guidance |
| neuron projection guidance |
| establishment of protein localization to membrane |
| synapse |
| mitotic cell cycle phase transition |
| cell cycle phase transition |
| nuclear division |
| ribosome biogenesis |
| negative regulation of mitotic cell cycle |
| cadherin binding |
| organelle fission |
| camera-type eye development |
| protein targeting |
| eye development |
| visual system development |
| sensory system development |
| axonogenesis |
| nucleobase-containing compound catabolic process |
| translation |
| peptide biosynthetic process |
| axon development |
| cell morphogenesis involved in neuron differentiation |
| establishment of protein localization to organelle |
| heterocycle catabolic process |
| cellular nitrogen compound catabolic process |
| aromatic compound catabolic process |
| ribonucleoprotein complex biogenesis |
| neuron projection morphogenesis |
| organic cyclic compound catabolic process |
| protein localization to membrane |
| plasma membrane bounded cell projection morphogenesis |
| cell projection morphogenesis |
| cell part morphogenesis |
| amide biosynthetic process |
| peptide metabolic process |
| sensory organ development |
| chemotaxis |
| taxis |
| cell morphogenesis involved in differentiation |
| negative regulation of cell cycle |
| mitotic cell cycle process |
| regulation of mitotic cell cycle |
| neuron projection development |
| mitotic cell cycle |
| mRNA metabolic process |
| viral process |
| cell morphogenesis |
| protein localization to organelle |
| organelle assembly |
| symbiotic process |
| cellular amide metabolic process |
| neuron development |
| interspecies interaction between organisms |
| cellular component morphogenesis |
| cellular protein-containing complex assembly |
| cellular macromolecule catabolic process |
| intracellular protein transport |
| cell cycle process |
| neuron differentiation |
| endoplasmic reticulum |
| macromolecule catabolic process |
| plasma membrane bounded cell projection organization |
| cell projection organization |
| regulation of cell cycle |
| locomotion |
| cell cycle |
| RNA binding |
| organonitrogen compound biosynthetic process |
| protein transport |
| intracellular transport |
| generation of neurons |
| peptide transport |
| movement of cell or subcellular component |
| protein-containing complex assembly |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| neurogenesis |
| cellular nitrogen compound biosynthetic process |
| cell development |
| RNA metabolic process |
| cellular macromolecule biosynthetic process |
| negative regulation of gene expression |
| macromolecule biosynthetic process |
| organic substance catabolic process |
| cellular catabolic process |
| establishment of localization in cell |
| nitrogen compound transport |
| protein-containing complex subunit organization |
| membrane |
| gene expression |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 1/1 |
| 909776.0 | 1/1 |
| bile duct | 28/28 |
| blood | 28/28 |
| bone | 26/26 |
| breast | 33/33 |
| central nervous system | 56/56 |
| cervix | 4/4 |
| colorectal | 17/17 |
| esophagus | 13/13 |
| fibroblast | 1/1 |
| gastric | 16/16 |
| kidney | 20/21 |
| liver | 20/20 |
| lung | 75/75 |
| lymphocyte | 16/16 |
| ovary | 26/26 |
| pancreas | 24/24 |
| peripheral nervous system | 16/16 |
| plasma cell | 14/15 |
| prostate | 1/1 |
| skin | 24/24 |
| soft tissue | 9/9 |
| thyroid | 2/2 |
| upper aerodigestive | 22/22 |
| urinary tract | 29/29 |
| uterus | 5/5 |
Expression Distribution