Entrez Summary: This gene encodes a stromal cell derived factor that is a member of the CREC protein family. The encoded protein contains six EF-hand motifs and calcium-binding motifs. This protein localizes to the Golgi lumen and may be involved in regulating calcium dependent cellular activities. [provided by RefSeq, Sep 2011].
UniProt Summary: N/A
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
zymogen granule exocytosis
bleb
UV protection
calcium-ion regulated exocytosis
Golgi lumen
cerebellum development
fat cell differentiation
metencephalon development
late endosome
response to ethanol
response to UV
hindbrain development
response to alcohol
response to antibiotic
response to light stimulus
response to radiation
response to toxic substance
regulated exocytosis
calcium ion binding
brain development
head development
exocytosis
central nervous system development
Golgi apparatus
secretion by cell
endoplasmic reticulum
response to drug
export from cell
identical protein binding
secretion
response to abiotic stimulus
response to oxygen-containing compound
vesicle-mediated transport
membrane
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739