Pfam Domains GO Terms
| Sugar tr |
| MFS 1 |
| nicotinate transport |
| nicotinate transmembrane transporter activity |
| urate transport |
| organic cation transmembrane transporter activity |
| NAD biosynthesis via nicotinamide riboside salvage pathway |
| NAD biosynthetic process |
| organic cation transport |
| pyridine nucleotide biosynthetic process |
| nicotinamide nucleotide biosynthetic process |
| nicotinamide nucleotide metabolic process |
| pyridine nucleotide metabolic process |
| pyridine-containing compound biosynthetic process |
| vitamin transport |
| pyridine-containing compound metabolic process |
| oxidoreduction coenzyme metabolic process |
| coenzyme biosynthetic process |
| monocarboxylic acid transport |
| drug transport |
| cofactor biosynthetic process |
| nucleotide biosynthetic process |
| nucleoside phosphate biosynthetic process |
| coenzyme metabolic process |
| organic acid transport |
| carboxylic acid transport |
| apical plasma membrane |
| cofactor metabolic process |
| nucleotide metabolic process |
| nucleoside phosphate metabolic process |
| organic anion transport |
| organophosphate biosynthetic process |
| nucleobase-containing small molecule metabolic process |
| anion transport |
| cation transport |
| organophosphate metabolic process |
| response to drug |
| nucleobase-containing compound biosynthetic process |
| heterocycle biosynthetic process |
| aromatic compound biosynthetic process |
| transmembrane transport |
| organic cyclic compound biosynthetic process |
| ion transport |
| integral component of plasma membrane |
| organonitrogen compound biosynthetic process |
| cellular nitrogen compound biosynthetic process |
| small molecule metabolic process |
| nitrogen compound transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| GSK591 2.6μM R03 exp128 | 1.77 |
| LB-100 2μM R05 exp210 | 2.04 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/25 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/15 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/14 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/7 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution