UniProt Summary: Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognizes their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity). {ECO:0000250, ECO:0000269|PubMed:12809675}.
Pfam DomainsGO Terms
Pfam Domains
Aa trans
GO Terms
amino acid:proton symporter activity
L-alanine transmembrane transporter activity
L-proline transmembrane transporter activity
proline transmembrane transport
glycine transmembrane transporter activity
L-alanine transport
proline transport
alanine transport
glycine transport
proton transmembrane transporter activity
neutral amino acid transport
amino acid transmembrane transporter activity
L-amino acid transport
amino acid transmembrane transport
amino acid transport
carboxylic acid transmembrane transport
organic acid transmembrane transport
proton transmembrane transport
drug transport
neurotransmitter transport
anion transmembrane transport
carboxylic acid transport
organic acid transport
lysosomal membrane
monovalent inorganic cation transport
organic anion transport
inorganic cation transmembrane transport
anion transport
cation transmembrane transport
inorganic ion transmembrane transport
cation transport
ion transmembrane transport
endoplasmic reticulum
response to drug
transmembrane transport
ion transport
nitrogen compound transport
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)