SLC7A14
Gene Information
- Official Symbol: SLC7A14
- Official Name: solute carrier family 7 member 14
- Aliases and Previous Symbols: N/A
- Entrez ID: 57709
- UniProt: Q8TBB6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene is predicted to encode a glycosylated, cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts, neural tissue, and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice, this gene is expressed in the photoreceptor layer of the retina where its expression increases over the course of retinal development and persists in the mature retina. [provided by RefSeq, Apr 2014].
- UniProt Summary: May be involved in arginine transport. {ECO:0000269|PubMed:22787143, ECO:0000269|PubMed:24670872}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 11786
- Expression level (log2 read counts): 3.62
SLC7A14 Expression in NALM6 Cells: 3.62
