Pfam Domains GO Terms
| SET |
| zf-MYND |
| histone-lysine N-methyltransferase activity |
| positive regulation of myoblast differentiation |
| positive regulation of myotube differentiation |
| skeletal muscle cell differentiation |
| regulation of myoblast differentiation |
| regulation of myotube differentiation |
| positive regulation of striated muscle cell differentiation |
| histone lysine methylation |
| positive regulation of muscle cell differentiation |
| peptidyl-lysine methylation |
| histone methylation |
| regulation of striated muscle cell differentiation |
| skeletal muscle tissue development |
| skeletal muscle organ development |
| protein methylation |
| protein alkylation |
| regulation of muscle cell differentiation |
| chromatin remodeling |
| transcription corepressor activity |
| macromolecule methylation |
| striated muscle tissue development |
| muscle organ development |
| muscle tissue development |
| methylation |
| peptidyl-lysine modification |
| histone modification |
| covalent chromatin modification |
| muscle structure development |
| heart development |
| chromatin organization |
| circulatory system development |
| peptidyl-amino acid modification |
| positive regulation of cell differentiation |
| chromosome organization |
| negative regulation of transcription, DNA-templated |
| negative regulation of nucleic acid-templated transcription |
| negative regulation of RNA biosynthetic process |
| negative regulation of RNA metabolic process |
| positive regulation of developmental process |
| negative regulation of cellular macromolecule biosynthetic process |
| negative regulation of nucleobase-containing compound metabolic process |
| DNA binding |
| negative regulation of macromolecule biosynthetic process |
| negative regulation of cellular biosynthetic process |
| negative regulation of biosynthetic process |
| negative regulation of gene expression |
| tissue development |
| regulation of cell differentiation |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/25 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/15 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/14 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/7 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution