UniProt Summary: Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.
Pfam DomainsGO Terms
Pfam Domains
PDZ
PH
GO Terms
dystrophin-associated glycoprotein complex
PDZ domain binding
intracellular
sarcolemma
structural molecule activity
calmodulin binding
muscle contraction
actin binding
synapse
muscle system process
cytoskeleton
focal adhesion
protein-containing complex
system process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)