UniProt Summary: Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration. {ECO:0000269|PubMed:20168327}.
Pfam DomainsGO Terms
Pfam Domains
TBCC
GO Terms
maintenance of Golgi location
maintenance of centrosome location
maintenance of organelle location
Golgi localization
spindle pole centrosome
centrosome localization
microtubule organizing center localization
maintenance of location in cell
regulation of cell shape
maintenance of location
regulation of cell morphogenesis
organelle localization
cell morphogenesis
cellular component morphogenesis
regulation of cell migration
regulation of cell motility
regulation of locomotion
regulation of cellular component movement
regulation of anatomical structure morphogenesis
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739