TLR10
Gene Information
- Official Symbol: TLR10
- Official Name: toll like receptor 10
- Aliases and Previous Symbols: N/A
- Entrez ID: 81793
- UniProt: Q9BXR5
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| TIR |
GO Terms
| toll-like receptor 10 signaling pathway |
| MyD88-dependent toll-like receptor signaling pathway |
| toll-like receptor signaling pathway |
| pattern recognition receptor signaling pathway |
| transmembrane signaling receptor activity |
| positive regulation of inflammatory response |
| regulation of cytokine secretion |
| innate immune response-activating signal transduction |
| activation of innate immune response |
| regulation of inflammatory response |
| positive regulation of innate immune response |
| positive regulation of response to biotic stimulus |
| regulation of innate immune response |
| regulation of protein secretion |
| positive regulation of defense response |
| regulation of peptide secretion |
| inflammatory response |
| positive regulation of multi-organism process |
| regulation of response to biotic stimulus |
| immune response-activating signal transduction |
| immune response-regulating signaling pathway |
| positive regulation of response to external stimulus |
| activation of immune response |
| regulation of cytokine production |
| regulation of protein transport |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| regulation of secretion by cell |
| regulation of defense response |
| innate immune response |
| regulation of multi-organism process |
| regulation of secretion |
| positive regulation of immune response |
| defense response to other organism |
| regulation of protein localization |
| identical protein binding |
| regulation of response to external stimulus |
| regulation of immune response |
| positive regulation of immune system process |
| response to other organism |
| response to external biotic stimulus |
| response to biotic stimulus |
| defense response |
| integral component of plasma membrane |
| regulation of response to stress |
| regulation of immune system process |
| regulation of transport |
| immune response |
| membrane |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 14110
- Expression level (log2 read counts): 5.3
Expression Distribution
TLR10 Expression in NALM6 Cells: 5.3
