UniProt Summary: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. {ECO:0000269|PubMed:10801128, ECO:0000269|PubMed:10903733, ECO:0000269|PubMed:10973284}.
Pfam DomainsGO Terms
Pfam Domains
BCMA-Tall bind
GO Terms
lymphocyte homeostasis
leukocyte homeostasis
endomembrane system
tumor necrosis factor-mediated signaling pathway
homeostasis of number of cells
signaling receptor activity
cellular response to tumor necrosis factor
response to tumor necrosis factor
adaptive immune response
cytokine-mediated signaling pathway
cellular response to cytokine stimulus
response to cytokine
homeostatic process
immune response
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)