UniProt Summary: Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with cellular components, and possesses weak ATPase activity. May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state. {ECO:0000269|PubMed:10101285, ECO:0000269|PubMed:11913975, ECO:0000269|PubMed:9324309}.
Pfam DomainsGO Terms
Pfam Domains
TPR 1
TPR 2
GO Terms
protein targeting to mitochondrion
heat shock protein binding
establishment of protein localization to mitochondrion
protein localization to mitochondrion
mitochondrial outer membrane
mitochondrial transport
protein targeting
establishment of protein localization to organelle
mitochondrion organization
protein localization to organelle
intracellular protein transport
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
establishment of localization in cell
nitrogen compound transport
membrane
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)