UniProt Summary: Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-288' of TSKS. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body. {ECO:0000269|PubMed:15733851, ECO:0000269|PubMed:19530700}.
Pfam DomainsGO Terms
Pfam Domains
Pkinase
Pkinase Tyr
GO Terms
acrosomal vesicle
motile cilium
spermatid development
spermatid differentiation
peptidyl-serine phosphorylation
peptidyl-serine modification
magnesium ion binding
germ cell development
protein-containing complex binding
cellular process involved in reproduction in multicellular organism
protein serine/threonine kinase activity
spermatogenesis
male gamete generation
developmental process involved in reproduction
gamete generation
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
peptidyl-amino acid modification
protein phosphorylation
multi-organism reproductive process
phosphorylation
reproductive process
reproduction
ATP binding
cell development
intracellular signal transduction
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)