UMODL1
Gene Information
- Official Symbol: UMODL1
- Official Name: uromodulin like 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 89766
- UniProt: Q5DID0
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| EGF CA |
| EMI |
| SEA |
| WAP |
| Zona pellucida |
GO Terms
| regulation of ovarian follicle development |
| cellular response to gonadotropin-releasing hormone |
| response to gonadotropin-releasing hormone |
| regulation of female gonad development |
| peptidase inhibitor activity |
| regulation of gonad development |
| adipose tissue development |
| single fertilization |
| regulation of reproductive process |
| fertilization |
| connective tissue development |
| negative regulation of peptidase activity |
| cellular response to peptide hormone stimulus |
| cellular response to peptide |
| negative regulation of proteolysis |
| response to peptide hormone |
| external side of plasma membrane |
| regulation of peptidase activity |
| negative regulation of hydrolase activity |
| response to peptide |
| cellular response to organonitrogen compound |
| cellular response to hormone stimulus |
| cellular response to nitrogen compound |
| calcium ion binding |
| regulation of proteolysis |
| negative regulation of catalytic activity |
| multicellular organismal reproductive process |
| sexual reproduction |
| multicellular organism reproduction |
| response to hormone |
| multi-organism reproductive process |
| response to organonitrogen compound |
| negative regulation of cellular protein metabolic process |
| cellular response to oxygen-containing compound |
| response to nitrogen compound |
| negative regulation of protein metabolic process |
| negative regulation of molecular function |
| cellular response to endogenous stimulus |
| regulation of hydrolase activity |
| reproductive process |
| reproduction |
| response to endogenous stimulus |
| regulation of apoptotic process |
| response to oxygen-containing compound |
| regulation of programmed cell death |
| extracellular space |
| regulation of cell death |
| tissue development |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Colchicine 0.009μM R05 exp215 | -1.74 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 10065
- Expression level (log2 read counts): 2.0
Expression Distribution
UMODL1 Expression in NALM6 Cells: 2.0
