UniProt Summary: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain.
Pfam DomainsGO Terms
Pfam Domains
UCR 6-4kD
GO Terms
respirasome
ubiquinol-cytochrome-c reductase activity
mitochondrial electron transport, ubiquinol to cytochrome c
electron transfer activity
mitochondrial ATP synthesis coupled electron transport
ATP synthesis coupled electron transport
respiratory electron transport chain
oxidative phosphorylation
cellular respiration
electron transport chain
ATP metabolic process
energy derivation by oxidation of organic compounds
mitochondrial inner membrane
generation of precursor metabolites and energy
oxidation-reduction process
phosphorylation
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739