UniProt Summary: Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre- ribosomal RNA transcription by RNA polymerase I. {ECO:0000269|PubMed:17699751}.
Pfam DomainsGO Terms
Pfam Domains
UTP15 C
WD40
GO Terms
positive regulation of ribosome biogenesis
positive regulation of rRNA processing
regulation of rRNA processing
regulation of ribosome biogenesis
positive regulation of transcription by RNA polymerase I
regulation of transcription by RNA polymerase I
fibrillar center
rRNA processing
rRNA metabolic process
ribosome biogenesis
ncRNA processing
ribonucleoprotein complex biogenesis
ncRNA metabolic process
positive regulation of cellular component biogenesis
nucleolus
RNA processing
regulation of cellular component biogenesis
endoplasmic reticulum
RNA binding
positive regulation of transcription, DNA-templated
positive regulation of nucleic acid-templated transcription
positive regulation of RNA biosynthetic process
RNA metabolic process
positive regulation of RNA metabolic process
positive regulation of nucleobase-containing compound metabolic process
positive regulation of macromolecule biosynthetic process
positive regulation of cellular biosynthetic process
positive regulation of gene expression
gene expression
positive regulation of biosynthetic process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)