Pfam Domains GO Terms
| V-SNARE |
| V-SNARE C |
| voluntary musculoskeletal movement |
| vesicle fusion with Golgi apparatus |
| Golgi ribbon formation |
| Golgi to vacuole transport |
| neuron projection terminus |
| SNAP receptor activity |
| intra-Golgi vesicle-mediated transport |
| protein targeting to vacuole |
| multicellular organismal movement |
| musculoskeletal movement |
| establishment of protein localization to vacuole |
| SNARE complex |
| ER to Golgi transport vesicle membrane |
| clathrin-coated vesicle |
| protein localization to vacuole |
| SNARE binding |
| autophagosome |
| vesicle fusion |
| organelle membrane fusion |
| retrograde transport, endosome to Golgi |
| trans-Golgi network membrane |
| organelle fusion |
| post-Golgi vesicle-mediated transport |
| late endosome membrane |
| synaptic vesicle |
| membrane fusion |
| Golgi organization |
| vacuolar transport |
| cytosolic transport |
| endoplasmic reticulum to Golgi vesicle-mediated transport |
| endosomal transport |
| autophagy |
| process utilizing autophagic mechanism |
| endosome |
| vesicle organization |
| protein targeting |
| neuronal cell body |
| Golgi vesicle transport |
| endomembrane system organization |
| establishment of protein localization to organelle |
| Golgi membrane |
| intracellular membrane-bounded organelle |
| perinuclear region of cytoplasm |
| protein localization to organelle |
| membrane organization |
| endoplasmic reticulum membrane |
| Golgi apparatus |
| intracellular protein transport |
| protein transport |
| intracellular transport |
| peptide transport |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| cellular catabolic process |
| establishment of localization in cell |
| nitrogen compound transport |
| vesicle-mediated transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Tanespimycin 14μM R08 exp527 | -1.73 |
| Talazoparib 0.006μM R06 exp299 | 1.78 |
| AICAR 240μM R03 exp116 | 1.83 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution