ZCCHC6
Gene Information
- Official Symbol: TUT7
- Official Name: terminal uridylyl transferase 7
- Aliases and Previous Symbols: N/A
- Entrez ID: 79670
- UniProt: Q5VYS8
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| PAP assoc |
GO Terms
| uridylyltransferase activity |
| regulation of transposition, RNA-mediated |
| polyuridylation-dependent mRNA catabolic process |
| RNA uridylyltransferase activity |
| negative regulation of transposition, RNA-mediated |
| RNA 3 uridylation |
| pre-miRNA processing |
| histone mRNA catabolic process |
| oocyte maturation |
| miRNA metabolic process |
| negative regulation of transposition |
| regulation of transposition |
| nuclear-transcribed mRNA poly(A) tail shortening |
| histone mRNA metabolic process |
| production of miRNAs involved in gene silencing by miRNA |
| miRNA binding |
| dsRNA processing |
| production of small RNA involved in gene silencing by RNA |
| oocyte development |
| oocyte differentiation |
| gene silencing by miRNA |
| posttranscriptional gene silencing by RNA |
| posttranscriptional gene silencing |
| nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
| oogenesis |
| gene silencing by RNA |
| female gamete generation |
| RNA 3-end processing |
| anatomical structure maturation |
| gene silencing |
| cell maturation |
| nuclear-transcribed mRNA catabolic process |
| mRNA catabolic process |
| regulation of gene expression, epigenetic |
| developmental maturation |
| RNA catabolic process |
| germ cell development |
| cellular process involved in reproduction in multicellular organism |
| nucleobase-containing compound catabolic process |
| ncRNA processing |
| heterocycle catabolic process |
| cellular nitrogen compound catabolic process |
| aromatic compound catabolic process |
| ncRNA metabolic process |
| organic cyclic compound catabolic process |
| posttranscriptional regulation of gene expression |
| modification-dependent macromolecule catabolic process |
| developmental process involved in reproduction |
| gamete generation |
| mRNA metabolic process |
| multicellular organismal reproductive process |
| sexual reproduction |
| zinc ion binding |
| multicellular organism reproduction |
| RNA processing |
| cellular macromolecule catabolic process |
| multi-organism reproductive process |
| macromolecule catabolic process |
| RNA binding |
| reproductive process |
| reproduction |
| cell development |
| RNA metabolic process |
| negative regulation of gene expression |
| organic substance catabolic process |
| cellular catabolic process |
| gene expression |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Adefovir 20μM R07 exp332 | 1.74 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 7007
- Expression level (log2 read counts): 5.65
Expression Distribution
ZCCHC6 Expression in NALM6 Cells: 5.65
