ZNF205
Gene Information
- Official Symbol: ZNF205
- Official Name: zinc finger protein 205
- Aliases and Previous Symbols: N/A
- Entrez ID: 7755
- UniProt: O95201
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: May be involved in transcriptional regulation.
Pfam Domains GO Terms
Pfam Domains
| zf-C2H2 |
| KRAB |
GO Terms
| positive regulation of hydrogen peroxide biosynthetic process |
| positive regulation of hydrogen peroxide metabolic process |
| positive regulation of cofactor metabolic process |
| regulation of hydrogen peroxide biosynthetic process |
| regulation of hydrogen peroxide metabolic process |
| positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway |
| regulation of cofactor metabolic process |
| regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway |
| positive regulation of reactive oxygen species biosynthetic process |
| regulation of mitochondrial membrane permeability |
| regulation of membrane permeability |
| regulation of reactive oxygen species biosynthetic process |
| positive regulation of reactive oxygen species metabolic process |
| positive regulation of mitochondrion organization |
| mitochondrial membrane organization |
| positive regulation of apoptotic signaling pathway |
| regulation of reactive oxygen species metabolic process |
| regulation of mitochondrion organization |
| mitochondrial transport |
| DNA-binding transcription repressor activity, RNA polymerase II-specific |
| RNA polymerase II regulatory region sequence-specific DNA binding |
| regulation of apoptotic signaling pathway |
| mitochondrion organization |
| positive regulation of organelle organization |
| positive regulation of apoptotic process |
| positive regulation of programmed cell death |
| positive regulation of cell death |
| zinc ion binding |
| membrane organization |
| negative regulation of transcription by RNA polymerase II |
| positive regulation of transport |
| negative regulation of transcription, DNA-templated |
| positive regulation of cellular component organization |
| negative regulation of nucleic acid-templated transcription |
| negative regulation of RNA biosynthetic process |
| mitochondrion |
| regulation of organelle organization |
| negative regulation of RNA metabolic process |
| negative regulation of cellular macromolecule biosynthetic process |
| negative regulation of nucleobase-containing compound metabolic process |
| negative regulation of macromolecule biosynthetic process |
| negative regulation of cellular biosynthetic process |
| regulation of apoptotic process |
| negative regulation of biosynthetic process |
| DNA-binding transcription factor activity, RNA polymerase II-specific |
| regulation of programmed cell death |
| positive regulation of signal transduction |
| regulation of cell death |
| negative regulation of gene expression |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of transport |
| positive regulation of cellular biosynthetic process |
| positive regulation of biosynthetic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 4279
- Expression level (log2 read counts): -2.21
Expression Distribution
ZNF205 Expression in NALM6 Cells: -2.21
